Inflammation reporter system
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United States of America Patent
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Sep 8, 2020
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Aug 3, 2017
app pub date -
Jul 31, 2014
filing date -
Jul 31, 2014
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Abstract
The present invention provides a method for detection of an inflammatory reaction, which comprises using a transformant or transgenic non-human animal transfected with a vector comprising a promoter for a gene encoding an inflammatory cytokine, a gene encoding a reporter protein, a gene encoding the inflammatory cytokine, and a gene encoding a proteolytic signal sequence to thereby detect an inflammatory reaction induced upon inflammatory stimulation in the transformant or in the transgenic non-human animal.
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