Compositions, methods and kits for treating complement related disorders
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United States of America Patent
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Oct 27, 2020
Grant Date -
Jul 27, 2017
app pub date -
Feb 28, 2017
filing date -
Aug 28, 2014
priority date (Note) -
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status (Latency Note)
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Abstract
Compositions, methods and kits are provided for treating complement related disorders in a subject with protein in combination having protein fusions of at least two of a CD46 protein, a CD55 protein and a CD59 protein or with a recombinant chimeric protein having at least two of a CD46 protein, a CD55 protein and a CD59 protein or with nucleic acids encoding these proteins. The composition negatively modulates classical and alternative complement pathways thereby treating complement related disorder such as macular degeneration, age-related macular degeneration, diabetic retinopathy, inflammatory bowel disease, thyroiditis, cryoglobulinaemia, fetal loss, organ graft rejection, cancer, etc.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- B08B:CLEANING IN GENERAL; PREVENTION OF FOULING IN GENE....
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- A47K:SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR
- A61P:THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDI....
- B25G:HANDLES FOR HAND IMPLEMENTS
- C07K:PEPTIDES
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