Process for producing 7-dehydrocholesterol and vitamin D3
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United States of America Patent
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Jun 25, 2019
Grant Date -
Jul 20, 2017
app pub date -
Oct 8, 2015
filing date -
Oct 8, 2014
priority date (Note) -
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Abstract
According to the present invention, there can be provided a process for producing 7-dehydrocholesterol (7DHC), comprising culturing, in a medium, a 7DHC-producing Labyrinthulea microorganism in which sterol 24-C-methyltransferase activity is reduced or lost as compared to a parent strain, allowing 7DHC to be produced and accumulated in the culture, and collecting the 7DHC from the culture; and a process for producing vitamin D3, comprising irradiating, with ultraviolet light, 7-dehydrocholesterol produced by the production process.
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