METHODS FOR THE TREATMENT OF TUMORS

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United States of America Patent

SERIAL NO

15301893

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is directed to methods of treating a tumor, in particular human tumors, including administering an effective amount of a MER tyrosine kinase inhibitor (MER TKI) to inhibit TKI signaling in a tumor. The use of a MER TKI in combination with a chemotherapeutic agent, wherein the MER TKI can be administered to a host with a cancer prior to, during, or after administration with a chemotherapeutic agent, provides for increased anti-tumor effects without an increase in the standard of care dosage of the chemotherapeutic agent.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF COLORADO1800 GRANT STREET 8TH FLOOR DENVER CO 80203

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
EARP,, III H Shelton Chapel Hill, US 2 1
FRYE, Stephen V Chapel Hill, US 11 76
GRAHAM, Douglas Kim Atlanta, US 8 48
WANG, Xiaodong Chapel Hill, US 544 6681

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