BIOMARKERS OF OXIDATIVE STRESS
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United States of America Patent
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Mar 22, 2017
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Jul 18, 2013
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Abstract
The present invention relates to a method for detecting cardiovascular oxidative stress in an individual, comprising detecting in a blood sample from the individual modification of a cysteine at position 45 of the β1-subunit of the human erythrocyte ATP-dependent Na+K+ pump protein or of an equivalent cysteine in a homologue or variant thereof. The invention further relates to a kit for detecting cardiovascular oxidative stress in an individual, the kit comprising at least one agent for detecting the presence of a modification in a cysteine at position 45 of the β1-subunit of the human erythrocyte ATP-dependent Na+K+ pump protein or of an equivalent cysteine in a homologue or variant thereof, wherein said modification is a result of oxidation.
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