NEW CRYSTAL FORM OF PANTOPRAZOLE SODIUM COMPOUND AND PREPARATION METHOD THEREFOR

Number of patents in Portfolio can not be more than 2000

United States of America Patent

SERIAL NO

15304861

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A novel crystalline form is defined by using diffraction angle 2θ° of X-ray powder diffraction pattern and characteristic peaks of differential scanning calorimetry (DSC). Pantoprazole Sodium solid is added to an alcohol solvent to form a suspension with a concentration of 0.05˜0.2 g/mL, and then an antioxidant is added to the suspension, completely dissolving the solid at a temperature of 15˜35° C., and a solventing-out agent is dropwise added to the solution under the application of ultrasonic wave, wherein the amount of the solventing-out agent is 3˜10 times (in volume) of the alcohol solvent; followed by cooling the solution down to 0˜5° C., continuing to stir for 1˜3 h, and suction filtrating obtained solid-liquid suspension to provide a novel crystalline form of Pantoprazole Sodium crystal after drying the product to constant weight.

First Claim

See full text

Other Claims data not available

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
TIANJIN UNIVERSITY300072 TIANJIN CITY NANKAI DISTRICT WEI JIN ROAD NO 92 TIANJIN CITY TIANJIN CITY 300072
HAINAN LINGKANG PHARMACEUTICAL CO LTDNO 16 YAOGU ERHENG ROAD YAOGU INDUSTRIAL PARK HAIKOU NATIONAL HIGH TECH INDUSTRIAL DEVELOPMENT ZONE HAIKOU CITY HAINAN PROVINCE 570318 HAIKOU CITY HAINAN 570318

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HAO, Hongxun Tianjin, CN 7 0
HOU, Baohong Tianjin, CN 13 0
JIANG, Shen Tianjin, CN 14 3
LV, Jun Haikou, Hainan, CN 24 94
TAO, Linggang Haikou, Hainan, CN 15 0
WANG, Jingkang Tianjin, CN 20 23
WANG, Yongli Tianjin, CN 23 41
WANG, Zhao Tianjin, CN 240 2466
XIE, Chuang Tianjin, CN 8 27
XU, Zhao Tianjin, CN 29 70
YIN, Qiuxiang Tianjin, CN 9 0

Cited Art Landscape

Load Citation

Patent Citation Ranking

  • 0 Citation Count
  • C07D Class
  • 0 % this patent is cited more than
  • 8 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges158718941835528419501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7081 - 90010020030040050060070080090010001100120013001400150016001700180019002000

Forward Cite Landscape

Load Citation