Method For Predicting Effectiveness Of Angiogenesis Inhibitor
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United States of America Patent
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app pub date -
Mar 16, 2017
filing date -
May 17, 2011
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Abstract
The purpose of the present invention is to provide a method for predicting the effectiveness of an angiogenesis inhibitor in a subject suffering from a tumor. Provided is a method comprising a step of testing for the presence or absence of an a mutation or loss of expression of B-Raf and PTEN in a sample of tumor tissue from the subject. By using the presence or absence of or a mutation or loss of expression of B-Raf and PTEN as an indicator, this method enables the antitumor effectiveness of the angiogenesis inhibitor to be predicted without administering the angiogenesis inhibitor to the subject.
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| Country | kind | publication No. | Filing Date |
|---|---|---|---|
| JP | B2 | JP5952810 | May 16, 2012 |
| WO | A1 | WO2012157672 | May 16, 2012 |
| EP | B1 | EP2711433 | May 16, 2012 |
| US | A1 | US20140148483 | May 16, 2012 |
| US | A1 | US20200199689 | Mar 04, 2020 |
| US | A1 | US20230212679 | Mar 11, 2022 |
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Patent Citation Ranking
- 13 Citation Count
- A61K Class
- 93.51 % this patent is cited more than
- 8 Age