PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES

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United States of America Patent

SERIAL NO

15231005

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Abstract

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The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS AGBASEL SUI
ASTEX THERAPEUTICS LIMITEDCAMBRIDGE CAMBRIDGESHIRE CB4 0QA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BESONG, Gilbert Cambridge, GB 16 32
BRAIN, Christopher Thomas Cambridge, US 30 283
BROOKS, Clinton A Durham, US 8 27
CONGREVE, Miles Stuart Cambridge, GB 132 1216
DAGOSTIN, Claudio Cambridge, GB 12 109
HE, Guo Framingham, US 18 120
HOU, Ying Cambridge, US 29 136
HOWARD, Steven Cambridge, GB 78 720
LAGU, Bharat Acton, US 67 464
LI, Yue Shanghai, CN 869 5176
LU, Yipin Emeryville, US 13 142
MORTENSON, Paul Cambridge, GB 9 26
SMITH, Troy Cambridge, US 42 210
SUNG, Moo Je Cambridge, US 20 270
WOODHEAD, Steven Cambridge, GB 9 28
WRONA, Wojciech Cambridge, US 16 164

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