BIOLOGICAL MARKER FOR EVALUATING THE IL-17 PRO-INFLAMMATORY FUNCTIONAL CONTRIBUTION DEPENDENT LEVEL IN AN INDIVIDUAL

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United States of America Patent

SERIAL NO

15316525

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Abstract

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The invention relates to an in vitro process for determining the functional IL-17 pro-inflammatory dependent level (IPDL) of a biological sample, comprising the following steps:

    a) measuring the level of an inflammatory marker produced by IL-17-sensitive cells incubated in the presence of a biological sample,b) measuring the level of said inflammatory marker produced by said cells incubated in the presence of a biological sample, in the presence of antibodies which neutralize the biological activity of IL-17, andc) determining the IPDL level, which is the difference between the level of said inflammatory marker measured in step a) and the level of said inflammatory marker measured in step b).

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Patent Owner(s)

Patent OwnerAddress
HOSPICES CIVILS DE LYON3 QUAI DES CELESTINS LYON CEDEX 2 69229
UNIVERSITE CLAUDE BERNARD LYON 143 BOULEVARD DU ONZE NOVEMBRE 1918 VILLEURBANNE 69100

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
MIOSSEC, Pierre Bron, FR 8 48
THIAM, Ndieme Lyon, FR 3 0

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