Tubular nanostructure targeted to cell membrane
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United States of America Patent
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Jun 16, 2020
Grant Date -
Jun 22, 2017
app pub date -
Mar 8, 2017
filing date -
Sep 15, 2008
priority date (Note) -
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Abstract
Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. The tubular nanostructure is configured to interact with a lipid bilayer membrane and form a pore in the lipid bilayer membrane. The tubular nanostructure may be targeted by including at least one ligand configured to bind to one or more cognates on the lipid bilayer membrane of a target cell.
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