METHOD FOR DETECTING OR TREATING TRIPLE NEGATIVE BREAST CANCER

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United States of America Patent

SERIAL NO

15127240

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Abstract

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A method of detecting triple negative breast cancer (TNBC) is provided. Overexpression of ICAM-1 is linked to an increased risk of TNBC. A composition of matter is also provided that binds an anti-ICAM˜1 antibody to a nanoparticle. The composition may be used as an imaging agent and/or a therapeutic targeting agent. A therapeutically active molecule may be bound to the composition to provide targeted therapy.

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Patent Owner(s)

Patent OwnerAddress
CHILDREN'S MEDICAL CENTER CORPORATION55 SHATTUCK STREET BOSTON MA 02115

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Auguste, Debra New York, US 8 6
Guo, Peng New York, US 71 535
Moses, Marsha A Boston, US 58 448

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