STABLE POLYMORPH FORM B OF TAPENTADOL HYDROCHLORIDE

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United States of America Patent

SERIAL NO

15118119

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure relates to Tapentadol Hydrochloride in the polymorphic crystalline Form B, which is substantially free of polymorphic Form A as well as essentially free of low alkyl carboxylic acids or esters of such acids. Furthermore, the present disclosure provides a process to produce this polymorphic Form B substantially free of Form A and its preparation and use for pharmaceutical compositions. This process as well as the specific crystalline form is uncommon, improved and industrially advantageous. Furthermore, the disclosure relates to pharmaceutical compositions and uses thereof.

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Patent Owner(s)

Patent OwnerAddress
AZAD PHARMACEUTICAL INGREDIENTS AG8200 SCHAFFHAUSEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BOCK, Dominique Anna Mülheim an der Ruhr, DE 1 0
HAFERKAMP, Sven Bochum, DE 3 0
MAIER, Thomas Stockach, DE 205 1047
PORSTMANN, Frank Stetten, CH 7 36

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