Methods for treating cancer by administering humanized pan-HER antibody compositions
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United States of America Patent
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Aug 28, 2018
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Jun 15, 2017
app pub date -
Nov 14, 2016
filing date -
May 2, 2012
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Abstract
The invention relates to humanized recombinant antibodies targeting the EGFR family receptors EGFR, HER2 and HER3, compositions comprising at least one humanized anti-EGFR antibody, at least one humanized anti-HER2 antibody and at least one humanized anti-HER3 antibody, and use of the antibody compositions for treatment of cancer. The invention also relates to the use of antibodies targeting multiple EGFR-family receptors to treat cancer (e.g., pancreatic cancer) and cancer that has acquired resistance to previous therapies.
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