NEW STRATEGIES FOR TREATING MELANOMA

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United States of America Patent

SERIAL NO

15300835

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a p53-activating agent capable of transferring wild-type tumor protein p53 (p53) from an inactive conformation into an active conformation capable of inducing apoptosis, for use in the treatment of melanoma, wherein said p53-activating agent is administered simultaneously or sequentially with a BRAF-inhibiting agent capable of inhibiting activity of serine/threonine-protein kinase B-Raf (BRAF) comprising an activating mutation.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT JULES BORDET1 RUE HÉGER-BORDET BRUXELLES 1000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AWADA, Ahmad Ternat, BE 193 219
GHANEM, Ghanem Drogenbos, BE 2 1
JOURNÉ, Fabrice Blaregnies, BE 1 1
KRAYEM, Mohammad Bruxelles, BE 1 1

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