METHOD FOR THE CHARACTERIZATION OF LIPOPROTEINS

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United States of America Patent

SERIAL NO

15039308

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Abstract

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An in vitro method for the characterization of lipoproteins in a sample, comprising obtaining a 2D diffusion-ordered 1H NMR spectrum of the sample and performing a surface fitting of a portion of the spectrum corresponding to the methyl signal using a plurality of model functions, each model function corresponding to a given particle size associated to a lipoprotein fraction and subclass and including at least one model parameter to be estimated during the fitting, the estimated model parameters being the set of model parameters for which the difference between the NMR signal and the model signal built as a linear combination of the model functions is minimized, wherein each model function is a triplet of lorentzian functions.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITAT ROVIRA I VIRGILI43003 TARRAGONA
INSTITUT D'INVESTIGACIO SANITARIA PERE VIRGILI43003 TARRAGONA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AMIGÓ, GRAU Núria Reus-Tarragona, ES 1 1
CORREIG, BLANCHAR Xavier Reus-Tarragona, ES 1 1
HERAS, IBÁÑEZ Mercedes Reus-Tarragona, ES 1 1
MALLOL, PARERA Roger Reus-Tarragona, ES 1 1
MASANA, MARÍN Lluís Tarragona, ES 1 1
PLANA, GIL Núria Tarragona, ES 1 1
RIBALTA, VIVES Josep Reus, Tarragona, ES 1 1
RODRÍGUEZ, MARTÍNEZ Miguel Ángel Vilaseca, Tarragona, ES 1 1

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