Methods and compositions for loading of polymerase complexes

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United States of America Patent

PATENT NO 10731211
APP PUB NO 20170159119A1
SERIAL NO

15354803

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Abstract

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The present disclosure provides methods, compositions, and systems for distributing polymerase compositions into array regions. In particular, the described methods, compositions, and systems utilize density differentials and/or additives to increase efficiency in the distribution of polymerase compositions to a surface as compared to methods utilizing only diffusion control.

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Patent Owner(s)

Patent OwnerAddress
PACIFIC BIOSCIENCES OF CALIFORNIA INC1305 O'BRIEN DRIVE MENLO PARK CA 94025

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hunkapiller, Michael San Carlos, US 8 554
Kamtekar, Satwik Redwood City, US 50 708
Miller, Erik San Francisco, US 88 1047
Popovich, Natasha Menlo Park, US 30 572
Sheikholeslami, Sassan San Francisco, US 7 46
Sun, Lei San Jose, US 350 2682

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