METHOD FOR FUSION EXPRESSION OF ION CHANNEL PROTEIN AND TRANSPORT PROTEIN AND PROTEIN FRAGMENT USED THEREFOR
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Nov 29, 2016
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Jun 5, 2014
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Abstract
The present invention provides a protein fragment for fusion expression of ion channel protein and transport protein. The protein fragment is a Bril protein fragment or a T4L protein fragment. Also provided is a method for preparing a fusion protein by inserting a Brit protein fragment or T4L protein fragment into the N-terminal, C-terminal or intramembrane loop region of the ion channel protein and transport protein so as to improve its, in-vitro stability and crystallizability.
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