METHOD FOR MANUFACTURING TRANSGENIC PLANT PRODUCING IMMUNOGENIC COMPLEX PROTEINS AND IMMUNOGENIC COMPLEX PROTEINS OBTAINED THEREFROM

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United States of America Patent

SERIAL NO

15376031

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Abstract

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The present invention relates to a method for manufacturing a transgenic plant producing immunogenic complex proteins and immunogenic complex proteins obtained therefrom and, more specifically, to a method for manufacturing a transgenic plant producing immunogenic complex proteins, a plant manufactured by the method, and immunogenic complex proteins obtained from the plant, wherein the method comprises the steps of: (a) manufacturing a transgenic plant expressing an antigen; (b) manufacturing a transgenic plant expressing an antibody specific to the antigen in step (a); and (c) cross-breeding the plants in steps (a) and (b) to manufacture a cross-bred plant. Immunogenic complex proteins can be mass-produced through the method for manufacturing a transgenic plant, comprising steps (a) to (c), and the transgenic plant manufactured by the method, of the present invention. Further, the immunogenic complex proteins (antigen-antibody complex) obtained from the plant have a gigantic four-dimensional structure, thereby having an excellent immune reaction boosting effect, thus exhibiting an excellent antibody producing capacity in a host animal, even without the use of an immune adjuvant.

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Patent Owner(s)

Patent OwnerAddress
CHUNG-ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION84 HEUKSEOK-RO DONGJAK-GU SEOUL 06974

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Deuk-su Seoul, KR 1 0
Ko, Kinarm Gyeonggi-do, KR 1 0
Ko, Kisung Daejeon, KR 4 2

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