BICYCLIC DERIVATIVE CONTAINING PYRIMIDINE RING, AND PREPARATION METHOD THEREFOR

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United States of America Patent

APP PUB NO 20160090374A1
SERIAL NO

14893517

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides: a bicyclic derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof; a preparation method therefor, a pharmaceutical composition comprising the same; and a use therefor. According to the present invention, the bicyclic compound derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof acts as a 5-HT4 receptor agonist, and thus can be usefully applied to the prevention or treatment of dysfunction in gastrointestinal motility, for example, gastrointestinal diseases such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, diabetic gastric atony and the like.

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Patent Owner(s)

  • YUHAN CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHA, Myung Hun Gyeonggi-do, KR 1 0
KIM, Dong Hoon Gyeonggi-do, KR 143 1024
KIM, Tae Kyun Gyeonggi-do, KR 116 1196
SIM, Jae Young Gyeonggi-do, KR 22 113
YOON, Young Ae Seoul, KR 5 0

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