CELL LOCATION UNIT, ARRAY, DEVICE AND FORMATION METHOD THEREOF
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United States of America Patent
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Jun 23, 2015
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Jun 23, 2014
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Abstract
The present disclosure provides a cell positioning unit, array, device and a method for manufacturing the same. The cell positioning unit comprises: a substrate; at least a pair of microelectrodes on the substrate, wherein the microelectrodes are disposed at intervals on a circumference such that pDEP force are generated in an area where tips of the microelectrodes aggregate, and wherein a voltage signal applied to at least one microelectrode has a phase difference with a voltage signal applied to another microelectrode; and a cell positioning hole on the microelectrodes, wherein the cell positioning hole has an accommodation space which exposes the pDEP force fields and accommodates a single cell. By applying an AC voltage signal having a certain amplitude, frequency and phase to the microelectrodes, cells will move to surfaces of the microelectrodes, such that a single cell can be accurately positioned to a certain place by means of the cell positioning hole and the microelectrodes.
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