Stable liquid formulations of cyclophosphamide and processes to prepare the same

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United States of America Patent

PATENT NO 11382923
APP PUB NO 20170143744A1
SERIAL NO

15402712

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to stable liquid pharmaceutical formulations of cyclophosphamide comprising cyclophosphamide and at least one pharmaceutically acceptable excipient wherein moisture content of the liquid formulation is less than about 2.0% by weight. The invention further relates to stable liquid formulations of cyclophosphamide prepared by a process comprising a step of reducing the moisture content from cyclophosphamide or liquid compositions of cyclophosphamide or both. The invention further relate to method of using such stable liquid formulations of cyclophosphamide for parenteral administration either as ready-to-use or ready-to-dilute for treating various cancer disorders.

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Patent OwnerAddress
AVYXA HOLDINGS LLC250 MUNOZ RIVERA AVENUE SUITE 310 SAN JUAN 00918

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhagwatwar, Harshal Hyderabad, IN 6 12
Chaurasiya, Akash Agra, IN 4 8
Garikipati, Svb Janardhan Visakhapatnam, IN 10 19
Patel, Bhavesh Vallabhbhai Hyderabad, IN 5 8
Pillai, Sumitra Ashok Ahmedabad, IN 5 18
Saha, Ananya Asansol, IN 6 8
Shaik, Riyaz Ahmed Hyderabad, IN 4 4

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