ANTIBODY FC VARIANTS
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United States of America Patent
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Sep 7, 2016
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Mar 29, 2011
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Abstract
The invention relates to engineered polypeptides comprising Fc variants and their uses. More specifically, Fc variants are described exhibiting reduced effector function. These variants cause a benefit for a patient suffering from a disease which could be treated with an antibody for which it is desirable to reduce the effector function elicited by antibodies.
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