TREATMENT OF CHRONIC KIDNEY DISEASE AND OTHER RENAL DYSFUNCTION USING A GDF15 MODULATOR

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United States of America Patent

APP PUB NO 20170137506A1
SERIAL NO

15320101

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides methods and compositions for treating a subject having a renal-related disorder, such as chronic kidney disease (CKD), end stage renal failure, diabetes, insulin resistance, kidney hypertrophy, kidney hypotrophy, polycystic kidney disease, proteinuria, hyperglycemia, hyperuricemia, gout, kidney stones, hypertension or hypertensive nephropathy, dyslipidemia, anemia and/or reduced erythropoietin production, iron deficiency or hyperfiltration. The methods and compositions use or contain a composition that reduces or inhibits GDF15 activity.

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Patent Owner(s)

Patent OwnerAddress
AVEO PHARMACEUTICALS INC30 WINTER STREET BOSTON MA 02108

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gyuris, Jeno Lincoln, US 63 604
Lerner, Lorena Newton Centre, US 30 101

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