PEPTIDES, AND METHODS AND APPARATUS UTILISING SAME

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United States of America Patent

SERIAL NO

15316339

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to peptides that are able to bind to anti-PLA2R antibodies. The peptides comprise the amino acid sequence K-X1-X2-X3-X4-X5-K-X6-X7-X8-X9-X10-X11-X12-X13-K (SEQ ID NO:2), in which both X1 and X13 may be cysteine residues. The peptides may have a length of up to 60 amino acid residues, or as little as 31 amino acid residues. The peptides are useful in the prevention or treatment of kidney disease, and methods of preventing or treating kidney disease by providing a therapeutically effective amount of a peptide to a subject, as well as devices for extra corporeal treatment of a patient's blood, are all provided. The invention also provides methods of determining levels of anti-PLA2R antibodies in a subject, and pharmaceutical compositions comprising a peptide and a pharmaceutically acceptable carrier.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF MANCHESTEROXFORD ROAD MANCHESTER M13 9PL

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brenchley, Paul Sale, Cheshire, GB 2 0
Fresquet, Maryline Sale, GB 2 0
Gummadova, Jennet Runcorn, Cheshire, GB 1 0
McKenzie, Edward High Peak, Derbyshire, GB 1 0

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