Fast method to analyse blood samples for the identification of hemoglobin variants using electron transfer dissociation
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United States of America Patent
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Jun 16, 2020
Grant Date -
May 11, 2017
app pub date -
Mar 31, 2015
filing date -
Mar 31, 2014
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Abstract
A method of screening or testing a sample is disclosed that comprises ionising a native human hemoglobin sample to generate parent or precursor ions, subjecting the parent or precursor ions to Electron Transfer Dissociation fragmentation so as to generate a plurality of fragment ions, mass analysing the fragment ions and determining whether or not the fragment ions include fragment ions which are indicative of a variant of hemoglobin.
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