SPATIAL MOLECULAR PROFILING OF SOLID BIOLOGICAL MASSES AND PROFILE STORAGE
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United States of America Patent
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Issued Date -
May 11, 2017
app pub date -
Jun 23, 2015
filing date -
Jun 30, 2014
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Abstract
Disclosed is a method for capturing the spatial molecular profiling of a biological mass formed from biological material, comprising the steps of: a) providing a transected biological mass, for example a tumour, the transection exposing at least a portion of the mass; b) providing a solid support of an area at least equalling the area of said portion of the mass; c) transferring biological material from the portion of the mass to the support to provide on the support a two dimensional imprint of the biological material present at the portion of the mass; and d) performing a biological assay of the transferred biological material from different predetermined locations of the imprint in order to determine the spatial molecular profile of the portion of the mass.
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