Multi-step separation process

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United States of America Patent

PATENT NO 10214475
APP PUB NO 20170130163A1
SERIAL NO

15411702

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Abstract

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The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which comprises: (a) purifying the feed mixture in a first chromatographic separation step using an eluent a mixture of water and a first organic solvent, to obtain an intermediate product; and (b) purifying the intermediate product in a second chromatographic separation step using as eluent a mixture of water and a second organic solvent, to obtain the PUFA product, wherein the second organic solvent is different from the first organic solvent and has a polarity index which differs from the polarity index of the first organic solvent by between 0.1 and 2.0, wherein the PUFA product is other than alpha-linolenic acid (ALA), gamma-linolenic acid (GLA), linoleic acid, an ALA mono- di- or triglyceride, a GLA mono- di- or triglyceride, a linoleic acid mono- di- or triglyceride, an ALA C1-C4 alkyl ester, a GLA C1-C4 alkyl ester or a linoleic acid C1-C4 alkyl ester or a mixture thereof.

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Patent Owner(s)

Patent OwnerAddress
BASF PHARMA (CALLANISH) LIMITEDCHEADLE CHESHIRE SK8 6QG

International Classification(s)

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  • 2017 Application Filing Year
  • C11B Class
  • 277 Applications Filed
  • 183 Patents Issued To-Date
  • 66.07 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kelliher, Adam Cheshire, GB 23 123
Morrison, Angus Cheshire, GB 30 125

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