ALPHA-V BETA-8 ANTIBODIES
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United States of America Patent
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Issued Date -
May 11, 2017
app pub date -
Jun 17, 2015
filing date -
Jun 17, 2014
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Abstract
Provided herein are antibodies specific for integrin αvβ8 that change the conformation of β8 so that, upon binding the ability of αvβ8 to induce release of active, mature TGFβ peptide is inhibited.
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