inhibitory peptides

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United States of America Patent

PATENT NO 10793598
APP PUB NO 20170129923A1
SERIAL NO

15321109

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Abstract

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Fusion peptides and methods of inhibiting GrB-EHITSN or a fragment thereof are provided. The fusion peptides include an NPF peptide and a cell-permeable peptide operably connected thereto. Fusion peptides and methods of inhibiting activity of GrB-EHITSN or fragment thereof are provided. An aspect includes a fusion peptide comprising an isolated NPF peptide comprising an amino acid sequence having at least 90% identity to SEQ ID NO: 2 and a cell-permeable peptide operably connected to the isolated NPF peptide, wherein the fusion peptide inhibits activity of GrB-EHITSN or a fragment thereof.

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Patent OwnerAddress
RUSH UNIVERSITY MEDICAL CENTER1653 WEST CONGRESS PARKWAY CHICAGO IL 60612

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  • 2015 Application Filing Year
  • A61K Class
  • 16157 Applications Filed
  • 11882 Patents Issued To-Date
  • 73.55 % Issued To-Date
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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Predescu, Dan Hinsdale, US 1 0
Predescu, Sanda Hinsdale, US 1 0

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