METHOD FOR IMPROVING SOLUBILITY OF PROTEIN AND PEPTIDE BY USING IMMUNOGLOGULIN FC FRAGMENT LINKAGE

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United States of America Patent

SERIAL NO

15129897

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Abstract

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The present invention relates to a method for improving the solubility of a physiologically active protein or peptide compared to that of a physiologically active protein or peptide which is not conjugated to an immunoglobulin Fc fragment, in which the method comprises conjugating the physiologically active protein or peptide to an immunoglobulin Fc fragment; and a composition for improving the solubility of a physiologically active protein or peptide, comprising an immunoglobulin Fc fragment, in which the composition improves the solubility compared to a composition without an immunoglobulin Fc fragment.

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Patent Owner(s)

Patent OwnerAddress
HANMI PHARM CO LTD214 MUHA-RO PALTAN-MYEON GYEONGGI-DO HWASEONG-SI 18536

International Classification(s)

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  • 2015 Application Filing Year
  • A61K Class
  • 16157 Applications Filed
  • 11882 Patents Issued To-Date
  • 73.55 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BAE, Sung Min Seongnam-si, KR 50 410
JUNG, Sung Youb Yongin-si, KR 86 704
KIM, Dae Jin Hwaseong-si, KR 95 825
KWON, Se Chang Seoul, KR 120 1146
LEE, Jong Soo Seongnam-si, KR 85 376
LIM, Hyung Kyu Hwaseong-si, KR 22 62

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Patent Citation Ranking

  • 1 Citation Count
  • A61K Class
  • 45.09 % this patent is cited more than
  • 8 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges763281956782001332911183139501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000

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