Use of oil and water emulsions for increasing B cell responses with modified Vaccinia Ankara virus

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United States of America Patent

PATENT NO 10653766
APP PUB NO 20170128561A1
SERIAL NO

15125388

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Abstract

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The invention relates to compositions, uses, and methods for inducing an immune response against a vaccinia virus. The addition of an oil and water emulsion to MVA can vastly increase the B cell response and particularly neutralizing antibodies against vaccinia virus and encoded recombinant antigens. Thus, the addition of an oil and water emulsion to MVA can increase the protective immune response. The invention encompasses administering a dose of an MVA in an oil and water emulsion to an animal, especially a human.

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Patent Owner(s)

Patent OwnerAddress
BAVARIAN NORDIC A/SHEJRESKOVVEJ 10A DK3490 KVISTGAARD DENMARK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheminay, Cédric Munich, DE 7 7
Steigerwald, Robin Munich, DE 32 48
Volkmann, Ariane Andechs, DE 10 68

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