INTERFERON ALPHA-INDUCED PHARMACODYNAMIC MARKERS AND USES THEREOF

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United States of America Patent

SERIAL NO

15290925

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Abstract

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The present invention encompasses type-I IFN and IFNα-induced PD marker expression profiles, kits, and methods for identifying such IFNα-induced PD marker expression profiles. The type-I IFN and IFNα-induced PD marker expression profiles may also be used in, for example, methods of treating patients having a type-I IFN or IFNα-mediated disorder, methods of monitoring disease progression of patients receiving treatment with a therapeutic agent that binds to and modulates IFNα activity, identifying patients as candidates to receive a therapeutic that binds to and neutralizes IFNα activity, and in diagnosing or providing a prognosis to patients having IFNα-induced disorders.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE LLCONE MEDIMMUNE WAY GAITHERSBURG MD 20878

International Classification(s)

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  • 2016 Application Filing Year
  • C12Q Class
  • 3975 Applications Filed
  • 2340 Patents Issued To-Date
  • 58.87 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CIBOTTI, RICARDO GAITHERSBURG, US 13 46
COYLE, ANTHONY GAITHERSBURG, US 42 360
JALLAL, BAHIJA GAITHERSBURG, US 33 267
KIENER, PETER GAITHERSURG, US 50 634
YAO, YIHONG GAITHERSBURG, US 52 114

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  • C12Q Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges2682212021779161049531101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +020040060080010001200140016001800200022002400260028003000

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