Enzymatically responsive magnetic particles and their use
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United States of America Patent
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Dec 8, 2020
Grant Date -
May 4, 2017
app pub date -
Apr 9, 2015
filing date -
Apr 9, 2014
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Abstract
The invention relates to an enzymatically responsive product that includes an amino acid residue conjugated to a magnetic particle, wherein the amino acid residue is phosphorylated or sulfated or comprises an ester-moiety linked via peptide bond. Compositions containing the enzymatically responsive product, and the use thereof for separating distinct types of mammalian cells (e.g., cancer cells from normal cells), for treating a cancerous condition, and imaging cancer cells are also disclosed.
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