CELL DELIVERY SYSTEM AND METHOD
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United States of America Patent
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Apr 27, 2017
app pub date -
Jun 9, 2015
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Jun 10, 2014
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Abstract
The present invention is directed to a cell delivery system for the delivery of materials including nucleic acids across a biological barrier and methods of use thereof. The cell delivery system of the invention comprises a microprotrusion array composed of a swellable and/or dissolvable polymer composition for use in the transport of a material across a biological barrier, wherein the material comprises nanoparticles formed from a nucleic acid complexed with an amphipathic cell penetrating peptide and wherein the microprotrusion array is loaded with the nanoparticles.
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