Mitochondrial preproteins as markers for Alzheimer's disease
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United States of America Patent
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Jul 21, 2020
Grant Date -
Apr 20, 2017
app pub date -
Mar 6, 2015
filing date -
Mar 7, 2014
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Abstract
The present invention is inter alia concerned with a method of diagnosing Alzheimer's disease in a patient, wherein said method is based on determining the amount of at least one premature mitochondrial protein. Further, the present invention relates to the use of such a protein as marker for Alzheimer's disease. Accordingly, antibodies binding to such a preprotein may be used for diagnosing Alzheimer's disease. The present invention is based on the finding that premature mitochondrial proteins accumulate in Alzheimer's disease.
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