GENE EXPRESSION MARKERS FOR PREDICTING OVERALL SURVIVAL IN SUBJECTS TREATED WITH SIPULEUCEL-T

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United States of America Patent

SERIAL NO

15268267

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Abstract

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Gene expression profiling in patients with mCRPC identifying genes that predict overall survival in response to treatment with sipuleucel-T, the method comprising the steps of (a) determining a gene expression level of a first biomarker; (b) determining a gene expression level of at least one additional biomarker different from the first biomarker; and (c) transforming the expression level of the first biomarker and the at least one additional biomarker into a first score corresponding to a probability of overall survival in response to treatment with sipuleucel-T.

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Patent Owner(s)

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DENDREON PHARMACEUTICALS LLC1700 SATURN WAY SEAL BEACH CA 90740

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fan, Li-Qun Bellevue, US 2 1
GuhaThakurta, Debraj Bellevue, US 4 22
Kandadi, Harini East Windsor, US 2 1
Sheikh, Nadeem A Seattle, US 2 1
Trager, James B Seattle, US 3 3

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