Methods and compositions for treating phenylketonuria

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United States of America Patent

PATENT NO 10792339
APP PUB NO 20170106054A1
SERIAL NO

15212009

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Abstract

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The present invention provides compositions and methods of treating hyperphenylalaninemia (e.g., phenylketonuria) in a subject in need thereof comprising administering to the subject an effective amount of a phenylalanine dehydrogenase (PheDH) polypeptide. The present invention also provides pharmaceutical formulations comprising PheDH for lowering the phenylalanine concentration in the subject (e.g., in the intestines and/or blood).

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Patent Owner(s)

Patent OwnerAddress
CHILDREN'S NATIONAL MEDICAL CENTER111 MICHIGAN AVENUE N W WASHINGTON DC 20010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cabrera-Luque, Juan Washington, US 2 2
Cunningham, Gary Washington, US 12 36
Kobayashi, Dione T Boston, US 2 2
McArthur, James G Concord, US 14 186
Summar, Marshall Washington, US 9 67

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