METHOD FOR DIAGNOSING AND TREATING MULTIPLE MYELOMA

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United States of America Patent

APP PUB NO 20170101684A1
SERIAL NO

15128082

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The disclosure is in the field of medical treatments and relates to the treatment of cancer, in particular, multiple myeloma (MM). Even more in particular, it provides means and methods for the improved treatment of certain subgroups of MM patients, more in particular, subjects with a poor prognosis. In a particular embodiment, the disclosure provides a method of treatment wherein subjects with a poor prognosis are selected and treated with a proteasome inhibitor such as Bortezomib. The disclosure further provides means and methods for identifying subjects with a poor prognosis. More in particular, the disclosure provides a composition comprising a proteasome inhibitor for use in the treatment of a subject with multiple myeloma when the subject has been diagnosed with an amp1q chromosomal aberration.

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Patent Owner(s)

Patent OwnerAddress
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAMROTTERDAM ROTTERDAM LIMBURG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sonneveld, Pieter Rotterdam, NL 8 1
Van, Vliet Martinus Hendrikus 's-Gravendeel, NL 4 0

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