Method for diagnosing colorectal cancer from a human feces sample by quantitative PCR, primers and kit
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United States of America Patent
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Feb 23, 2021
Grant Date -
Apr 6, 2017
app pub date -
Mar 3, 2015
filing date -
Mar 3, 2014
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Abstract
The present invention relates to the field of detection of colorectal cancer (CRC). Specifically it relates to methods for the early detection, risk screening and monitoring of CRC and/or adenomatous polyps in a human subject based on the quantification of one or more 16S rDNA bacterial sequences in feces. It further relates to the use of said bacterial sequences as biomarkers of colorectal cancer and/or adenomatous polyps; to a kit comprising a reagent and instructions for the quantification of said bacterial sequences; and to nucleic acids for the quantification of said 16S rDNA bacterial sequences.
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