EXPRESSION PROFILING FOR CANCERS TREATED WITH ANTI-ANGIOGENIC THERAPY

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United States of America Patent

SERIAL NO

15311618

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Abstract

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The present invention relates to a cancer sub-type. Provided are methods for determining clinical prognosis of a subject with cancer, selecting whether to administer an anti-angiogenic therapeutic agent to a subject with cancer and predicting responsiveness of a subject with cancer to an anti-angiogenic therapeutic agent. The methods are based on assessing from the expression level of biomarkers disclosed herein whether the cancer belongs to the sub-type. Companion methods of treating cancer and agents for use in treating cancer are also provided.

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Patent Owner(s)

Patent OwnerAddress
ALMAC DIAGNOSTICS LIMITEDCRAIGAVON BT63 5QD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DAVISON, Timothy Hillsborough, GB 31 588
DEHARO, Steve Belfast, GB 11 101
DONEGAN, Sinead Belfast, GB 3 14
GOURLEY, Charlie Dumfermline, GB 5 68
HARKIN, Denis Paul Dromore, GB 13 111
HILL, Laura Lisburn, GB 5 6
JELLEMA, Gera Portadown, GB 2 13
KEATING, Katherine Magherafelt, GB 1 0
KENNEDY, Richard Belfast, GB 29 312
MCCAVIGAN, Andrena Derryadd, GB 7 74
PATTERSON, Fionnuala Hauxton, GB 9 101

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