COMPOSITIONS AND METHODS FOR MODULATION OF SMN2 SPLICING

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United States of America Patent

APP PUB NO 20170088835A1
SERIAL NO

15267408

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a cell, tissue or animal. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders, including spinal muscular atrophy.

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Patent Owner(s)

Patent OwnerAddress
BIOGEN MA INC225 BINNEY STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baker, Brenda F Carlsbad, US 129 3917
Hua, Yimin Jericho, US 30 407
Krainer, Adrian R Huntington Station, US 24 415

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