IRINOTECAN HYDROCHLORIDE COMPOSITE PHOSPHOLIPID COMPOSITION, PREPARATION METHOD AND USE THEREOF

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United States of America Patent

SERIAL NO

15124626

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Abstract

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An irinotecan hydrochloride composite phospholipid composition, preparation method and uses thereof in the preparation of drugs for treating tumors or drug resistant tumors. The composite phospholipid composition comprises irinotecan hydrochloride, composite phospholipid, cholesterol, long-circulating membrane material, surfactant and a buffer medium. The composition improves stability of lipid formulation and the anti-tumor effect of irinotecan hydrochloride, and can overcome multidrug resistance of a tumor.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES201203 555 ZHANGJIANG ROAD ZHANGJIANG PUDONG NEW AREA SHANGHAI SHANGHAI CITY SHANGHAI CITY 201203
SHANGHAI JINGFENG PHARMACEUTICAL CO LTD200120 ROOM 3301 LIFE INSURANCE BUILDING 707 ZHANG YANG ROAD SHANGHAI PUDONG NEW AREA MUNICIPAL DISTRICT SHANGHAI CITY 200120

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHEN, Lingli Pudong Shanghai, CN 8 11
GU, Wangwen Pudong Shanghai, CN 1 1
LI, Yaping Pudong Shanghai, CN 15 51
ZHANG, Zhiwen Pudong Shanghai, CN 64 2484
ZHENG, Zhaolei Pudong Shanghai, CN 1 1

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