Modifying messenger RNA stability in plant transformations

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United States of America Patent

PATENT NO 10837024
APP PUB NO 20170081672A1
SERIAL NO

15056544

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Abstract

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Materials and methods for genome engineering through transient expression of a targeted nuclease are described herein. For example, the methods described herein can include introducing into a cell a messenger RNA (mRNA) that encodes a nuclease targeted to a selected sequence within the cell, where the stability of the mRNA is modified by the addition of untranslated regions (UTRs).

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CELLECTIS75013 PARIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Luo, Song Chicago, US 38 195
Stoddard, Thomas St. Louis Park, US 12 22

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