TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS

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United States of America Patent

SERIAL NO

15160706

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Abstract

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Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.

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Patent Owner(s)

Patent OwnerAddress
PROTHENA BIOSCIENCES LIMITEDDUBLIN 2 D02 T804

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
SALDANHA, JOSÉ ENFIELD, GB 6 8
SCHENK, DALE B BURLINGAME, US 134 5655
SEUBERT, PETER A SAN FRANCISCO, US 33 1397
WALL, JONATHAN KNOXVILLE, US 68 2873

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