CANCER STEM CELL PROLIFERATION INHIBITOR

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United States of America Patent

SERIAL NO

15312484

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Abstract

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The present invention aims to provide a growth inhibitor for cancer stem cells resistant to existing anticancer drug therapies, which growth inhibitor acts on the cells through growth inhibition and apoptosis. The growth inhibitor for cancer stem cells contains a retinoid agonist, preferably tamibarotene, alone or in combination with a rexinoid agonist, preferably bexarotene, as an effective component(s). The growth inhibitor for cancer stem cells enhances the effects of various anticancer drugs when the growth inhibitor is used in combination with the anticancer drugs.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY3-1 KASUMIGASEKI 1-CHOME CHIYODA-KU TOKYO 1008921 ?1008921
TMRC CO LTD1-12-12 KITASHINJUKU SHINJUKU-KU TOKYO 1690074 ?1690074

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
EKIMOTO, Hisao Tokyo, JP 18 90
KURISAKI, Akira Tsukuba-shi, JP 3 2
TAKADA, Hitomi Tsukuba-shi, JP 2 2
WANG, Ying Ying Tsukuba-shi, JP 12 43

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