ERBB2 SIGNALING AND NERVE REGENERATION

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20170058046A1
SERIAL NO

15308267

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Use of an inhibitor of the ErbB2 receptor for treatment or repair of nerves and/or nerve tissues is provided. The inhibitor includes an antibody, in particular, a monoclonal antibody, for example, Herceptin. A medicament for treatment or repair of nerves and/or nerve tissues can be formulated which includes an inhibitor of the ErbB2 receptor. A pharmaceutical kit may include a medicament having an inhibitor of the ErbB2 receptor and dosing instructions for administrating the medicament for treatment or repair of nerves and/or nerve tissues. Also provided are uses of an inhibitor of the ErbB2 receptor for increasing axon regeneration, preventing neuron or glial cell death, and/or stimulating Schwann cell proliferation in a nerve stump.

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Patent Owner(s)

Patent OwnerAddress
THE HOSPITAL FOR SICK CHILDRENTORONTO ON M5G 1X8

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BORSCHEL, Gregory H Toronto, CA 6 78
GORDON, Tessa Toronto, CA 5 34
HENDRY, James M Toronto, CA 4 32
PLACHETA, Eva Vienna, AT 3 14

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