Methods and Compositions for Inhibiting Clostridium difficile Spore Germination and Outgrowth

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United States of America Patent

APP PUB NO 20170056419A1
SERIAL NO

15133437

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Abstract

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Certain bile acids, including novel bile acids, and derivatives thereof can be used to inhibit the germination of C. difficile spores and/or the growth of C. difficile cells. The methods and compositions of the invention are useful for preventing and treating C. difficile-associated diseases, including but not limited to C. difficile colitis.

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Patent Owner(s)

Patent OwnerAddress
TUFTS UNIVERSITYBALLOU HALL MEDFORD MA 02155

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sonenshein, Abraham L Brookline, US 7 130
Sorg, Joseph College Station, US 2 24

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