Methods and Pharmaceutical Compositions for the Treatment of Diseases Mediated by the NRP-1/OBR Complex Signaling Pathway

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United States of America Patent

APP PUB NO 20170051062A1
SERIAL NO

15119401

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Abstract

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The present invention relates to methods and pharmaceutical compositions for the treatment of diseases mediated by the NRP-1/OBR complex signaling pathway. In particular, the present invention relates to a method for treating a disease selected from the group consisting of cancers, obesity and obesity related diseases, anorexia, autoimmune diseases and infectious diseases in a subject in need thereof comprising administering the subject with a therapeutically effective amount of an antagonist of the NRP-1/OBR signaling pathway.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)3 RUE MICHEL ANGE PARIS 75016
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES25 RUE LEBLANC BÂTIMENT LE PONANT D PARIS 75015
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)101 RUE DE TOLBIAC PARIS F-75013
UNIVERSITE PARIS DESCARTES75270 PARIS CEDEX 06
UNIVERSITE DE BOURGOGNEMAISON DE L'UNIVERSITÉ ESPLANADE ERASME DIJON 21000
UNIVERSITE GRENOBLE ALPES621 AVENUE CENTRALE SAINT MARTIN D'HERES 38400
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP)3 AVENUE VICTORIA PARIS F-75004
FONDATION IMAGINE24 BOULEVARD DU MONTPARNASSE PARIS 75015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Belaid-Choucair, Zakia Paris, FR 4 5
Cochet, Claude Grenoble Cedex 9, FR 9 15
Filhol-Cochet, Odile Grenoble Cedex 9, FR 5 11
Garrido-Fleury, Carmen Dijon Cedex, FR 6 5
Hermine, Olivier Paris, FR 35 115
Seigneuric, Renaud Dijon Cedex, FR 5 5

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