Method to Enhance an Immune Response of Nucleic Acid Vaccination
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United States of America Patent
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Nov 8, 2016
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Jul 5, 2002
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Abstract
A composition comprising liposomes associated with a nucleic acid operatively encoding an antigenic protein and with an assistor protein, wherein the assistor protein shares at least one epitope with the antigenic protein, and wherein the nucleic acid and said assistor protein are associated with the same liposomes is described. The composition provides an improved immune response compared to mixtures of liposomes some of which are associated with the nucleic acid and some of which are associated with the assistor protein.
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