PIK3CA FUSIONS

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United States of America Patent

APP PUB NO 20170044622A1
SERIAL NO

15304656

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) gene fusions, and fragments of those gene fusions. The invention further provides methods of diagnosing and treating diseases or disorders associated with PIK3CA fusions, such as conditions mediated by PIK3CA aberrant expression or activity, or overexpression of PIK3CA.

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Patent Owner(s)

Patent OwnerAddress
BLUEPRINT MEDICINES CORPORATIONCAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cerami, Ethan G Winchester, US 6 43
Lengauer, Christoph Cambridge, US 14 64
Stransky, Nicolas Charlestown, US 19 64

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